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TRAF6 functions as a tumor suppressor in myeloid malignancies by directly targeting MYC oncogenic activity.
Cell Stem Cell. 2022 Feb 3;29(2):298-314.e9. doi: 10.1016/j.stem.2021.12.007. Epub 2022 Jan 18.
Cell Stem Cell. 2022.
PMID: 35045331
Free PMC article.
Inactivation of p53 provides a competitive advantage to del(5q) myelodysplastic syndrome hematopoietic stem cells during inflammation.
Muto T, Walker CS, Agarwal P, Vick E, Sampson A, Choi K, Niederkorn M, Ishikawa C, Hueneman K, Varney M, Starczynowski DT.
Muto T, et al. Among authors: walker cs.
Haematologica. 2023 Oct 1;108(10):2715-2729. doi: 10.3324/haematol.2022.282349.
Haematologica. 2023.
PMID: 37102608
Free PMC article.
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TRAF6 Mediates Basal Activation of NF-κB Necessary for Hematopoietic Stem Cell Homeostasis.
Fang J, Muto T, Kleppe M, Bolanos LC, Hueneman KM, Walker CS, Sampson L, Wellendorf AM, Chetal K, Choi K, Salomonis N, Choi Y, Zheng Y, Cancelas JA, Levine RL, Starczynowski DT.
Fang J, et al. Among authors: walker cs.
Cell Rep. 2018 Jan 30;22(5):1250-1262. doi: 10.1016/j.celrep.2018.01.013.
Cell Rep. 2018.
PMID: 29386112
Free PMC article.
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Adaptive response to inflammation contributes to sustained myelopoiesis and confers a competitive advantage in myelodysplastic syndrome HSCs.
Muto T, Walker CS, Choi K, Hueneman K, Smith MA, Gul Z, Garcia-Manero G, Ma A, Zheng Y, Starczynowski DT.
Muto T, et al. Among authors: walker cs.
Nat Immunol. 2020 May;21(5):535-545. doi: 10.1038/s41590-020-0663-z. Epub 2020 Apr 20.
Nat Immunol. 2020.
PMID: 32313245
Free PMC article.
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